Title:
Bidialysis on line: a new solution for ipercatabolic or high body weight haemodialysis patients

Splendiani Giorgio¹ ;Splendiani Giorgio¹ ;Splendiani Giorgio¹ ;Splendiani Giorgio¹ ;Splendiani Giorgio¹ ;Splendiani Giorgio¹

Rome

E-mail address corresponding author:
splendiani@med.uniroma2.it

Background:
We just experimented, in patients with high body weight, the simultaneous use of two cuprophan hemodialyzers in sequence (DFS) in haemodialysis, each one connected separately to fresh dialysate and we concluded that there was an advantage in urea clearance, osmolarity stability and reduction of side effects. The principal aims of this new study was, using both diffusion and convection technique, obtain an increase in solute removal, without side effects, the patient's well being and without increase of global costs.

Methods:
We used two hemodialyzers in sequence, each one connected separately to fresh dialysate, the first was a low flux polysulphone, the second was an high flux polysulphone with a reinfusion on line of 200 ml/min between the first and the second hemodialyzers. We studied ten symptomatic ipercatabolic patients with high body weight and compared the results to conventional haemodialysis.

Results:
After the first hemodialyzers modification of smalls molecules occurred in the plasma composition. In the second hemodialyzer, smalls molecules depuration continued and we obtained also a b2 microglobulin removal. The Kt/V increased from 1.11 to 1.9 (79%).

Conclusion:
We conclude that Bidialysis on line is an advantage in blood purification and reduction of side effects in ipercatabolic or high body weight patients.

Subject:
Dialysis technologies

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