Title:
Therapeutic plasma exchange (TPE) with Haemonetics PCS for the treatment of acute hypertriglyceridemia

A.Griskevicius¹ ;A.Griskevicius¹ ;A.Griskevicius¹

Lithuania' ne ''

E-mail address corresponding author:
Antanas.Griskevicius@santa.lt

Background:
The aim of the present study was to retrospectively analyse results of TPE in patients transferred to our hospital for severe acute hypertriglyceridemia.

Methods:
TPE was carried out using centrifugation with intermittent flow methodology the Haemonetic PCS to separate plasma from blood. The anticoagulation of a heparin bolus followed by citrate infusion during the session. Substitution was performed with 5 %, 10 % human albumin solution, fresh frozen plasma and elektrolyte. 10-20 ml of 10 % Calcium gluconate were administered per liter of plasma protein substitution fluid.

Results:
We performed a retrospective analysis of 12 patients who underwent TPE during 2000-2005 may. Blood samples from all patients exhibited the characteristics features of lactescent and creamy appearance. In a total of 18 TPE sessions, on average 2040+242 ml of plasma (i.e., about 1 patients plasma volume) were treated per session. On admission, the mean triglycerids (TG)and total cholesterol (TCH) levels were 5625,4+2447,8 mg/dl and 833,6+571,6 mg/dl, respectively. Diabetes mellitus was an underlying condition in 7 patients. History of alcohol consumption prior to this event was traced in 1 patient.

Conclusion:
In summary TPE sufficed to substantially the bulk of triglycerids in acutely exacerbated hyperlipidemia sindrome.

Subject:
Apheresis

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